The action of echis carinatus venom on the blood coagulation system. Demonstration of an activator of factor X
نویسندگان
چکیده
منابع مشابه
The action of Echis carinatus venom on the blood coagulation system. Demonstration of an activator of factor X.
It is shown that Echis carinatus venom activates both coagulation factor II and coagulation factor X. The activation of both proenzymes by the venom is Ca++-dependent; phospholipids are not necessary. The activation of factor II by the venom is a slow process and, in the absence of factor X, the clotting activity towards fibrinogen is generated only very slowly. Because Echis carinatus venom cl...
متن کاملBlood Coagulation Induced by Iranian Saw-Scaled Viper (Echis Carinatus) Venom: Identification, Purification and Characterization of a Prothrombin Activator
Objective(s): Echis carinatus is one of the venomous snakes in Iran. The venom of Iranian Echis carinatus is a rich source of protein with various factors affecting the plasma protein and blood coagulation factor. Some of these proteins exhibit types of enzymatic activities. However, other items are proteins with no enzymatic activity. Materials and Methods: In order to study the mechanism ...
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ژورنال
عنوان ژورنال: Thrombosis Research
سال: 1984
ISSN: 0049-3848
DOI: 10.1016/0049-3848(84)90307-4